All products / DC31263
ONT-093
Pack sizes and prices
| Pack size | Price |
|---|---|
| 100 mg | $850 USDRequest a quote / confirm availability → |
| 250 mg | $1,350 USDRequest a quote / confirm availability → |
| 1 g | $2,800 USDRequest a quote / confirm availability → |
Confirm stock, lead time, shipping and final quotation with our team.
Product overview
ONT-093, also known as OC-144-093, is an orally bioavailable P-glycoprotein pump inhibitor, for the potential reversal of multidrug resistance in patients undergoing cancer chemotherapy. ONT-093 could inhibit P-gp and reverse multidrug resistance at nM concentrations with no effect on paclitaxel pharmacokinetics. OC144-093 is the least non-specifically toxic Pgp inhibitor described to date, with an average cytostatic IC50 of >60 microM in 15 cell types. OC144-093 may represent an ideal candidate for use in enhancement of AED blood-brain barrier penetration.
For research use only. Results depend on experimental conditions and do not constitute a performance guarantee.
Identity and specifications
| Catalog number | DC31263 |
|---|---|
| Product name | ONT-093 |
| CAS | 216227-54-2 |
| Molecular formula | C32H38N4O |
| Molecular weight | 494.67 |
| Purity | >98% |
| SMILES | CCOC/C=C/c1ccc(-c2nc(-c3ccc(NC(C)C)cc3)c(-c3ccc(NC(C)C)cc3)[nH]2)cc1 |
Source-listed specifications; the batch COA applies.
Source and product documents
The supplier source is linked below. Contact us for COA, SDS and batch-specific documents.
DC Chemicals — ONT-093 (DC31263)