All products / DC20252
CAT. NO. DC20252
NRX-252114
Pack sizes and prices
| Pack size | Price |
|---|---|
| 10 mg | $1,500 USDRequest a quote / confirm availability → |
Confirm stock, lead time, shipping and final quotation with our team.
Product overview
NRX-252114 is a potent enhancer of the interaction between β-catenin and its cognate E3 ligase, SCFβ-TrCP. It significantly strengthens the binding of the pSer33/S37A β-catenin peptide to β-TrCP, exhibiting an EC50 of 6.5 nM and a Kd of 0.4 nM. NRX-252114 also induces the degradation of mutant β-catenin.
For research use only. Results depend on experimental conditions and do not constitute a performance guarantee.
Identity and specifications
| Catalog number | DC20252 |
|---|---|
| Product name | NRX-252114 |
| CAS | 2763260-39-3 |
| Molecular formula | C22H12Cl2F3N3O2S |
| Molecular weight | 510.31579208374 |
| Purity | >98% |
| SMILES | N#Cc1cccc2c1CN(C(=O)c1c(Sc3c(Cl)cccc3Cl)cc(C(F)(F)F)[nH]c1=O)C2 |
Source-listed specifications; the batch COA applies.
Source and product documents
The supplier source is linked below. Contact us for COA, SDS and batch-specific documents.
DC Chemicals — NRX-252114 (DC20252)