All products / DC11002
CAT. NO. DC11002
NTN21277(Gefitinib-based PROTAC 3)
Pack sizes and prices
| Pack size | Price |
|---|---|
| 100 mg | $950 USDRequest a quote / confirm availability → |
| 250 mg | $1,700 USDRequest a quote / confirm availability → |
| 1 g | $3,500 USDRequest a quote / confirm availability → |
Confirm stock, lead time, shipping and final quotation with our team.
Product overview
Gefitinib-based PROTAC 3, conjugating an EGFR binding element to a VHL ligand via a linker, induces EGFR degradation with DC50s of 11.7 nM and 22.3 nM in HCC827(exon 19 del) and H3255 (L858R mutantion) cells, respectively.
For research use only. Results depend on experimental conditions and do not constitute a performance guarantee.
Identity and specifications
| Catalog number | DC11002 |
|---|---|
| Product name | NTN21277(Gefitinib-based PROTAC 3) |
| CAS | 2230821-27-7 |
| Molecular formula | C47H57ClFN7O8S |
| Molecular weight | 934.522 |
| Purity | >98% |
| SMILES | COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCCCOCCOCCC(=O)N[C@@H](C(=O)N1C[C@@H](O)C[C@@H]1C(=O)NCc1ccc(-c2scnc2C)cc1)C(C)(C)C |
Source-listed specifications; the batch COA applies.
Source and product documents
The supplier source is linked below. Contact us for COA, SDS and batch-specific documents.
DC Chemicals — NTN21277(Gefitinib-based PROTAC 3) (DC11002)