DC Chemicals

DC99010 · Updated 28 October 2026

CICL-1 (L829)

Instructions for Use

Before use

Check the supplied lot number, batch COA, approved SDS, quantity and retest date. Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light.

For small quantities of viscous or oily lipid, volumetric transfer can reduce weighing losses. Confirm solvent compatibility and solubility before preparing a stock; calculated volumes do not establish solubility.

Stock-solution planning

Volume (mL) = mass (mg) × 1000 / [molecular weight × concentration (mM)].

Mass10 mM20 mM
10 mg0.9868 mL0.4934 mL
25 mg2.4669 mL1.2335 mL
50 mg4.9339 mL2.4669 mL
100 mg9.8678 mL4.9339 mL

Literature formulation reference

ComponentDC Chemicals productMolecular weightMolar ratioMass at 1 µmol total lipid (mg)
L829 / CICL-1DC990101013.4Not assignedNot calculable from disclosed data
Targeting ligand-lipid conjugateNot uniquely mappedNot establishedNot assignedNot calculable from disclosed data
Other three lipid componentsNot uniquely mappedNot establishedNot assignedNot calculable from disclosed data

The molecular weight shown for CICL-1 is a catalog value. Complete five-lipid identity, proportions and N/P await Supplementary Table S1; no patent formulation is substituted.

Read the complete study conditions, biological results, tolerability and figures →

References

  1. Hunter TL et al. In vivo CAR T cell generation to treat cancer and autoimmune disease. Science 388, 1311-1317 (2025). DOI: 10.1126/science.ads8473.