DC99010 · Updated 28 October 2026
CICL-1 (L829)
Product Datasheet
CICL-1 (catalog alias L829) is an ionizable lipid for targeted RNA-delivery research. The cited L829 study reports in vivo CAR expression, B-cell depletion and leukemia-model activity using antibody-targeted LNPs, with a serious adverse event in a repeat-dose primate study. The catalog lipid is supplied for research; the reported outcomes depend on the complete LNP, targeting ligand and RNA cargo.
| CAS No. | Not available |
| Chemical Name | CICL-1 (L829) |
| Synonyms | L-829, L 829, Capstan-lipid-CICL-1, Capstanlipid CICL1, CICL1, CICL 1, CICL-1, Lipid 829, L-829, L 829, Compound A-11, DC60860 |
| SMILES | CCCCCCCCC(=O)OCC(COC(=O)CCCCCCCC)CC(=O)OCCN(CCOC(=O)CC(COC(=O)CCCCCCCC)COC(=O)CCCCCCCC)C(=O)OCCN(C)C |
| Formula | C55H100O14N2 |
| M.Wt | 1013.40 |
| Purity | >95% by ELSD-HPLC |
| Storage | Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication |
Research evidence
Read detailed Formulation & Performance
Specifications are catalog specifications, not batch test results.