DC67546 · Updated 27 October 2026

ALC-0307

Product Datasheet

ALC-0307 is an ionizable lipid explicitly identified in published antibody-targeted mRNA-LNP research. A separate official announcement identifies ALC-0307 and ALC-0159 in the personalized k-abe gene-editing program.

CAS No.	Not available
Chemical Name	ALC-0307
Synonyms	ALC0307， ALC 0307
SMILES	CCCCCCCCC(CCCCCCCC)OC(=O)CCCCCCCN(CCCCCCCC(=O)OC(CCCCCCCC)CCCCCCCC)CCCN(C)C
Formula	C55H110O4N2
M.Wt	863.5
Purity	>95% by ELSD-HPLC
Storage	Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light.
Shipping condition	Ships from Shanghai. Pure lipid is stable during ice-pack transport.
Publication	Tombácz I, et al. Highly efficient CD4+ T cell targeting and genetic recombination using engineered CD4+ cell-homing mRNA-LNPs. Molecular Therapy 29 (2021), 3293–3304. Acuitas Therapeutics. Official May 16, 2025 ASGCT announcement, p2 (lipid identity confirmation). Musunuru K, et al. Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease. NEJM 392 (2025), 2235–2243.

Research evidence

Read detailed Formulation & Performance

Specifications are catalog specifications, not batch test results.