Literature-reported formulation composition
Component: DOTMA | mol%: 50 | Role: cationic_lipid
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DOTMA
Literature records
Search the tables and observations reproduced from the product literature guide. Rows may represent measurements, recipes or experimental context; they are not all independent experiments.
Literature-reported formulation composition
Component: DPPC | mol%: 19.5 | Role: Helper phospholipid
Literature-reported formulation composition
Component: cholesterol | mol%: 30 | Role: Sterol
Literature-reported formulation composition
Component: DSPE-PEG(2k)-OMe | mol%: 0.5 | Role: PEG lipid
Literature-reported formulation composition
Component: Reported total | mol%: 100 | Role: Source values retained
Reported observation
Literature-reported Antibody response Higher SV-specific total IgG, IgG1, IgG2b and IgG2c versus SV alone/comparators Two SC vaccinations; blood day 28; Figs. 2–4
Reported observation
Literature-reported Th1 cytokine IFN-gamma 60-fold higher than SV + CpG ODN group; IL-2 higher than CpG ODN or alum Splenocytes 10 days after boost; Fig. 4
Reported observation
Literature-reported Protection Homologous and heterologous influenza challenge protection reported; graph values not reconstructed Mouse challenge; Fig. 5
Reported observation
Literature-reported Safety markers No significant spleen-weight, IL-6/IL-12 p40 or AST/ALT increase versus stated controls SC adjuvant conditions; Fig. 6