DC59126 · Updated 27 October 2026
Genevant CL1
Instructions for Use
Before use
Check the supplied lot number, batch COA, approved SDS, quantity and retest date. Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light.
For small quantities of viscous or oily lipid, volumetric transfer can reduce weighing losses. Confirm solvent compatibility and solubility before preparing a stock; calculated volumes do not establish solubility.
Stock-solution planning
Volume (mL) = mass (mg) × 1000 / [molecular weight × concentration (mM)].
| Mass | 10 mM | 20 mM |
|---|---|---|
| 10 mg | 1.7007 mL | 0.8503 mL |
| 25 mg | 4.2517 mL | 2.1259 mL |
| 50 mg | 8.5034 mL | 4.2517 mL |
| 100 mg | 17.0068 mL | 8.5034 mL |
Literature formulation reference
| Component | DC Chemicals product | Molecular weight | Molar ratio | Mass at 1 µmol total lipid (mg) |
|---|---|---|---|---|
| Lipid 10 / Genevant CL1 | DC59126 | 588.0 | 54.6 | Not calculable from disclosed data |
| DSPC | DC57005 | 790.15 | 10.9 | Not calculable from disclosed data |
| Cholesterol | DCD-041 | 386.65 | 32.8 | Not calculable from disclosed data |
| PEG-conjugated lipid (anchor unspecified) | Not uniquely mapped | Not established | 1.6 | Not calculable from disclosed data |
The component table describes the main mRNA ratio. siRNA uses a different ratio. PEG anchor identity and N/P are not specified in the reviewed main text; the ratios total 99.9 or 100.1 because of source rounding.
Read the complete study conditions, biological results, tolerability and figures →