DC Chemicals

DC59010 · Updated 27 October 2026

C14-4

Instructions for Use

Before use

Check the supplied lot number, batch COA, approved SDS, quantity and retest date. Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light.

For small quantities of viscous or oily lipid, volumetric transfer can reduce weighing losses. Confirm solvent compatibility and solubility before preparing a stock; calculated volumes do not establish solubility.

Stock-solution planning

Volume (mL) = mass (mg) × 1000 / [molecular weight × concentration (mM)].

Mass10 mM20 mM
10 mg0.7324 mL0.3662 mL
25 mg1.8311 mL0.9155 mL
50 mg3.6622 mL1.8311 mL
100 mg7.3244 mL3.6622 mL

Literature formulation reference

ComponentDC Chemicals productMolecular weightMolar ratioMass at 1 µmol total lipid (mg)
C14-4DC590101365.335Not calculable from disclosed data
DOPE (as abbreviated in the source)Not uniquely mappedNot established16Not calculable from disclosed data
CholesterolDCD-041386.6546.5Not calculable from disclosed data
C14-PEG (exact anchor unverified)Not uniquely mappedNot established2.5Not calculable from disclosed data

Reported molar composition 35:16:46.5:2.5. The source expands DOPE inconsistently: dioleoyl in Results and distearoyl in Methods. The exact PEG anchor is not verified. N/P and lipid:RNA mass ratio were not verified; do not assume 10:1 or substitute DMG-PEG2000.

Read the complete study conditions, biological results, tolerability and figures →

References

  1. Billingsley MM et al. Nano Letters 20, 1578–1589 (2020). DOI 10.1021/acs.nanolett.9b04246.
  2. Supporting Information, Table S3 and Figures S1–S3.